Автор: Hui Kimko and Stephen B. Duffull
Название: Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective
Издательство: CRC Press
Год: 2002
ISBN: 978-0824708627
Серия: Drugs and the Pharmaceutical Sciences (Book 127)
Язык: English
Формат: pdf
Размер: 14,1 mb
Страниц: 424

The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.